์•Œ๋ฆผ
๋’ค๋กœ

 




์žฅ๋น„ ์ด์šฉ ์„œ๋น„์Šค





๋ณด์œ  ์žฅ๋น„ ์†Œ๊ฐœ

*์žฅ๋น„ ์‚ฌ์ง„ ํด๋ฆญ ์‹œ ZEUS(์žฅ๋น„ํ™œ์šฉ์ข…ํ•ฉํฌํ„ธ)๋กœ ์ด๋™ํ•ฉ๋‹ˆ๋‹ค. 




์ƒ๋ฌผ๋ถ„์ž๋ฌผ์งˆ ์ƒํ˜ธ์ž‘์šฉ ๋ฐ˜์‘ ๋ถ„์„๊ธฐ(Biomolecule Interaction Analysis System)

์ œ์ž‘์‚ฌ๋ช…:Sartorius
๋ชจ๋ธ๋ช…:OCTET R4
ํ•ญ์ฒด·๋‹จ๋ฐฑ์งˆ ๊ฐ„ ๊ฒฐํ•ฉ์„ ์‹ค์‹œ๊ฐ„์œผ๋กœ ๋ถ„์„ํ•˜๋Š” ๋ผ๋ฒจ ํ”„๋ฆฌ ๊ธฐ๋ฐ˜์˜ ์†Œํ˜• ๋ฐ”์ด์˜ค ๋ถ„์„ ์žฅ๋น„.

ํ‘œ๋ฉด ํ”Œ๋ผ์ฆˆ๋ชฌ ๊ณต๋ช… ๋ถ„์„ ๊ธฐ๊ธฐ(Surface Plasmon Resonance Instrument)

์ œ์ž‘์‚ฌ๋ช…: iCLUEBIO
๋ชจ๋ธ๋ช…: iMSPR-Pro2X
๋ถ„์ž ๊ฐ„ ์ƒํ˜ธ์ž‘์šฉ์„ ์‹ค์‹œ๊ฐ„์œผ๋กœ ์ •๋ฐ€ ๋ถ„์„ํ•˜๋Š” ํ‘œ๋ฉด ํ”Œ๋ผ์ฆˆ๋ชฌ ๊ณต๋ช…(SPR) ๊ธฐ๋ฐ˜์˜ ๋ผ๋ฒจ ํ”„๋ฆฌ ๋ฐ”์ด์˜ค์„ผ์„œ ์žฅ๋น„.
์ดˆ๊ณ ์••์•ก์ฒดํฌ๋กœ๋งˆํ† ๊ทธ๋ž˜ํ”ผ(UHPLC system)

์ œ์ž‘์‚ฌ๋ช…: ThermoFisher Scienfic
๋ชจ๋ธ๋ช…: Thermo Scientific™ Vanquish™ Flex Quaternary UHPLC
๋‹ค์–‘ํ•œ ์šฉ๋งค ์กฐํ•ฉ์œผ๋กœ ๋ณต์žกํ•œ ์‹œ๋ฃŒ๋ฅผ ๊ณ ํ•ด์ƒ๋„๋กœ ๋ถ„๋ฆฌ·๋ถ„์„ํ•˜๋Š” quaternary ๋ฐฉ์‹์˜ ์ดˆ๊ณ ์„ฑ๋Šฅ ์•ก์ฒดํฌ๋กœ๋งˆํ† ๊ทธ๋ž˜ํ”ผ ์‹œ์Šคํ…œ.





Gel ์ด๋ฏธ์ง€ ๋ถ„์„ ์‹œ์Šคํ…œ
(Gel imaging system)

์ œ์ž‘์‚ฌ๋ช…: Vilber
๋ชจ๋ธ๋ช…: BioPrintCX4
DNA/RNA ๋ฐ ๋‹จ๋ฐฑ์งˆ gel์„ ์ดฌ์˜ํ•˜๊ณ  ํ˜•๊ด‘ ์‹ ํ˜ธ๋ฅผ ๊ธฐ๋ฐ˜์œผ๋กœ ๋ฐด๋“œ๋ฅผ ์ •๋Ÿ‰ ๋ถ„์„ํ•˜๋Š” gel ์ด๋ฏธ์ง€ ๋ถ„์„ ์‹œ์Šคํ…œ


์‹ค์‹œ๊ฐ„ ์œ ์ „์ž ์ฆํญ๊ธฐ
(Real Time PCR system)

์ œ์ž‘์‚ฌ๋ช…: ThermoFisher Scientific
๋ชจ๋ธ๋ช…: QuantStudio 6 PRO
๋‹ค์–‘ํ•œ ํ˜•๊ด‘ ๊ฒ€์ถœ ์ฑ„๋„์„ ๊ธฐ๋ฐ˜์œผ๋กœ ์œ ์ „์ž ๋ฐœํ˜„์„ ์ •๋ฐ€ํ•˜๊ฒŒ ์ •๋Ÿ‰ ๋ถ„์„ํ•˜๋Š” real-time PCR ์‹œ์Šคํ…œ.


์ค‘ํ•ฉํšจ์†Œ์—ฐ์‡„๋ฐ˜์‘๊ธฐ(PCR system)

์ œ์ž‘์‚ฌ๋ช…: QIAGEN 
๋ชจ๋ธ๋ช…: QIAamplifer 96
96well ํฌ๋ฉง์—์„œ DNA ์ฆํญ์„ ์•ˆ์ •์ ์œผ๋กœ ์ˆ˜ํ–‰ํ•˜๋Š” ๊ณ ์„ฑ๋Šฅ PCR thermal cycler

 





๋งˆ์ดํฌ๋กœํ”Œ๋ ˆ์ดํŠธ๋ฆฌ๋”๊ธฐ(Microplate reader)


์ œ์ž‘์‚ฌ๋ช…: PerkinElmer

๋ชจ๋ธ๋ช…: VICTOR NIVO

ํ˜•๊ด‘, ๋ฐœ๊ด‘, ํก๊ด‘ ์‹ ํ˜ธ๋ฅผ ์ธก์ •ํ•˜์—ฌ ์„ธํฌ ๋ฐ ์ƒํ™”ํ•™ ๋ฐ˜์‘์„ ์ •๋Ÿ‰ ๋ถ„์„ํ•˜๋Š” ๋งˆ์ดํฌ๋กœํ”Œ๋ ˆ์ดํŠธ ๋ฆฌ๋”.




๋ฏธ์„ธ์šฉ๋Ÿ‰ UV-Vis ๋ถ„๊ด‘๊ด‘๋„๊ณ„

(UV-Vis Spectrophotometer)


์ œ์ž‘์‚ฌ๋ช…:ThermoFisher Scientific
๋ชจ๋ธ๋ช…:  NanoDrop One
๊ทน์†Œ๋Ÿ‰ ์‹œ๋ฃŒ์˜ ํก๊ด‘๋„๋ฅผ ์ธก์ •ํ•˜์—ฌ DNA, RNA ๋ฐ ๋‹จ๋ฐฑ์งˆ ๋†๋„๋ฅผ ์ •๋Ÿ‰ ๋ถ„์„ํ•˜๋Š” ๋งˆ์ดํฌ๋กœ๋ณผ๋ฅจ ๋ถ„๊ด‘๊ด‘๋„๊ณ„.

์กฐ์งํฌ๋งค๊ธฐ

(Embedding Center)


์ œ์ž‘์‚ฌ๋ช…:Leica
๋ชจ๋ธ๋ช…: HistoCore Arcadia
ํŒŒ๋ผํ•€ ์ฒ˜๋ฆฌ๋œ ์กฐ์ง ํ‘œ๋ณธ์„ ํฌ๋งคํ•˜์—ฌ, ๋ณ‘๋ฆฌ์กฐ์ง ์Šฌ๋ผ์ด๋“œ ์ œ์ž‘์„ ์œ„ํ•ด ์ผ์ •ํ•œ ๊ฒฝ๋„์˜ ํŒŒ๋ผํ•€ ์กฐ์ง ๋ธ”๋ก์„ ์ œ์ž‘ํ•˜๋Š” ์žฅ๋น„.






์ž๋™์กฐ์ง์ ˆํŽธ๊ธฐ
(Automatic Rotary Microtome)

์ œ์ž‘์‚ฌ๋ช…:Leica
๋ชจ๋ธ๋ช…: HistoCore AUTOCUT
์กฐ์ง ์ƒ˜ํ”Œ์„ ์ผ์ •ํ•œ ๋‘๊ป˜๋กœ ์ •๋ฐ€ ์ ˆ๋‹จํ•˜์—ฌ ๋ณ‘๋ฆฌ ๋ถ„์„์šฉ ์Šฌ๋ผ์ด๋“œ๋ฅผ ์ œ์ž‘ํ•˜๋Š” ์ž๋™ ์กฐ์ง์ ˆํŽธ ์žฅ๋น„.
์กฐ์งํŒŒ์‡„๊ธฐ(Homogenize)

์ œ์ž‘์‚ฌ๋ช…:QIAGEN
๋ชจ๋ธ๋ช…: TissueLyzer II

Steel, tungsten carbide, or glass bead๋ฅผ ์ด์šฉํ•˜์—ฌ ์ƒ๋ฌผํ•™์  ์‹œ๋ฃŒ๋ฅผ ๊ณ ์† ๊ต๋ฐ˜์œผ๋กœ ํŒŒ์‡„ํ•ด ๊ท ์งˆํ™”ํ•˜์—ฌ ํ•ต์‚ฐ๊ณผ ๋‹จ๋ฐฑ์งˆ ์ถ”์ถœ์„ ์œ„ํ•œ ์‹œ๋ฃŒ๋ฅผ ์ค€๋น„ํ•˜๋Š” ์žฅ๋น„.



์ง„ํƒ•์„ธํฌ๋ฐฐ์–‘๊ธฐ
(Shaking incubator)

์ œ์ž‘์‚ฌ๋ช…:Eppendorf
๋ชจ๋ธ๋ช…: S41i
์˜จ๋„์™€ COโ‚‚ ํ™˜๊ฒฝ์„ ์œ ์ง€ํ•˜๋ฉด์„œ ๋™์‹œ์— ์ง„ํƒ• ๋ฐฐ์–‘์ด ๊ฐ€๋Šฅํ•œ ์„ธํฌ ๋ฐฐ์–‘์šฉ ์ธํ๋ฒ ์ดํ„ฐ.






Oโ‚‚ ์กฐ์ ˆ ์„ธํฌ๋ฐฐ์–‘๊ธฐ
(Oโ‚‚ regulation incubator)

์ œ์ž‘์‚ฌ๋ช…:NUAIRE
๋ชจ๋ธ๋ช…: NU-5831E  
์˜จ๋„์™€ COโ‚‚ ๋ฐ Oโ‚‚ ๋†๋„๋ฅผ ์ •ํ•˜๊ฒŒ ์ œ์–ด ๊ฐ€๋Šฅํ•˜์—ฌ  ์ €์‚ฐ์†Œ ์กฐ๊ฑด์„ ํฌํ•จํ•œ ์„ธํฌ ๋ฐฐ์–‘ ํ™˜๊ฒฝ์„ ๊ตฌํ˜„ํ•˜๋Š” ์ธํ๋ฒ ์ดํ„ฐ

COโ‚‚ ์„ธํฌ๋ฐฐ์–‘๊ธฐ
(COโ‚‚ incubator)

์ œ์ž‘์‚ฌ๋ช…:NUAIRE
๋ชจ๋ธ๋ช…: NU-5810E
์˜จ๋„์™€ COโ‚‚ ๋†๋„๋ฅผ ์•ˆ์ •์ ์œผ๋กœ ์œ ์ง€ํ•˜์—ฌ ์„ธํฌ๋ฅผ ๋ฐฐ์–‘ํ•˜๋Š” COโ‚‚ ์ธํ๋ฒ ์ดํ„ฐ.

์„ธํฌ ์ž„ํ”ผ๋˜์Šค ๋ชจ๋‹ˆํ„ฐ๋ง ์‹œ์Šคํ…œ
(Cell impedance monitoring system)

์ œ์ž‘์‚ฌ๋ช…:CELLAMES
๋ชจ๋ธ๋ช…: CIMS-16
์„ธํฌ์˜ ์ „๊ธฐ์  ์ž„ํ”ผ๋˜์Šค๋ฅผ ์ธก์ •ํ•˜์—ฌ ์ฆ์‹, ๋ถ€์ฐฉ, ๋…์„ฑ ๋ฐ˜์‘ ๋“ฑ์„ ์‹ค์‹œ๊ฐ„·๋น„ํŒŒ๊ดด์ ์œผ๋กœ ๋ถ„์„ํ•˜๋Š” ์„ธํฌ ๋ถ„์„ ์‹œ์Šคํ…œ.




 


์‹ค์‹œ๊ฐ„ OCR ์ธก์ • ์‹œ์Šคํ…œ
(RealTime OCR Measurement System)

์ œ์ž‘์‚ฌ๋ช…: Lucid Scientific
๋ชจ๋ธ๋ช…: RESIPHER-32
ํ‘œ์ค€ ์ธํ๋ฒ ์ดํ„ฐ ๋‚ด์—์„œ ํ‘œ์ค€ 96well plate์— ์„ธํฌ ๋“ฑ์„ ๋ฐฐ์–‘ํ•˜๋Š” ๋™์•ˆ Oxygen Consumption Rate(OCR)๋ฅผ ์ธก์ •ํ•˜์—ฌ ์‹ค์‹œ๊ฐ„·๋น„ํŒŒ๊ดด์ ์œผ๋กœ ์„ธํฌ ๋Œ€์‚ฌ ํ™œ๋™์„๋ชจ๋‹ˆํ„ฐ๋งํ•  ์ˆ˜ ์žˆ๋Š” ์žฅ๋น„		ํ˜ˆ์•ก๊ฐ€์Šค๋ถ„์„๊ธฐ
(Blood Gas Analyzer)

์ œ์ž‘์‚ฌ๋ช…:Siemens
๋ชจ๋ธ๋ช…: RAPIDLAB 348
ํ˜ˆ์•ก์˜ pH, pCOโ‚‚, pOโ‚‚ ๋“ฑ์„ ์ธก์ •ํ•˜์—ฌ ์‚ฐ-์—ผ๊ธฐ ์ƒํƒœ์™€ ๊ฐ€์Šค ๊ตํ™˜ ์ƒํƒœ๋ฅผ ์‹ ์†ํ•˜๊ฒŒ ๋ถ„์„ํ•˜๋Š” ํ˜ˆ์•ก๊ฐ€์Šค๋ถ„์„๊ธฐ 
์›ฐํ”Œ๋ ˆ์ดํŠธ ๋””์ŠคํŽœ์„œ
(Well Plate dispenser)

์ œ์ž‘์‚ฌ๋ช…:ThermoFisher Scientific
๋ชจ๋ธ๋ช…: Multidrop COMBI+
๋‹ค์–‘ํ•œ ์šฉ๋Ÿ‰์˜ ์•ก์ฒด๋ฅผ ๊ณ ์†์œผ๋กœ ๋ถ„์ฃผํ•˜์—ฌ ๋Œ€๋Ÿ‰ ์‹œ๋ฃŒ๋ฅผ ํšจ์œจ์ ์œผ๋กœ ์ฒ˜๋ฆฌํ•˜๋Š” ์•ก์ฒด ๋ถ„์ฃผ ์žฅ๋น„